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Bus from Syracuse to Buffalo

Book your bus ticket to Buffalo from Syracuse today

Duration 3 hours 20 minutes (fastest time)

Departures Up to 1 service per day

Why travel with megabus?

Power outlets onboard*

Express service

Green certified

* Subject to availability

Syracuse to Buffalo bus details

Our route M24 bus stops at 4 stops between Syracuse and Buffalo. The bus sets off from Syracuse Regional Transit Center and drops you off at Megabus Bus Stop - Gate 13 - Downtown Terminal at 181 Ellicott St

Syracuse

Arrivals and departures are located at the curbside in front of the William F Walsh Regional Transportation Center on the north side of the city. Connections are available to the CENTRO regional bus system.

Buffalo

Megabus.com and Fullington Trailways arrivals and departures are located in the Metropolitan Transportation Center terminal building at 181 Ellicott Street.


Plan your bus trip to Buffalo

Bus from Syracuse to Buffalo with megabus

Our Buses

We are very proud of our fleet of state of the art buses.

* Subject to availability

Frequently Asked Questions

How long does it take to travel from Syracuse to Buffalo by bus?

The fastest bus from Syracuse to Buffalo takes 3 hours 20 minutes

When is the first bus from Syracuse to Buffalo?

The earliest bus from Syracuse to Buffalo leaves at 2:00 PM

When is the last bus from Syracuse to Buffalo?

The latest bus from Syracuse to Buffalo leaves at 2:00 PM

How many daily bus trips are there from Syracuse to Buffalo?

Megabus runs up to 1 trips per day from Syracuse to Buffalo